Mark Mondesir was born in Stepney, London, on 12 December 1964.

Mondesir began his career in 1984 as part of Ian Carr's workshops at the Weekend Arts Center. Mondesir worked with Courtney Pine between 1985 and 1989 and recorded with Kevin Eubanks in 1991.

I n the 1990s, Mark Mondesir accompanied musicians who were visiting the UK; these included Art Farmer, Hermeto Pascoal and John Scofield. Mondesir played with Pee Wee Ellis's Assembly in 1996. In the 1990s and early 2000s, he was part of bands led by pianist Julian Joseph.

Mondesir was part of guitarist John McLaughlin's 4th Dimension Band for their "To the One" album, which was recorded in 2009.

He played with the Jazz Warriors, the Jazz Crusaders, the Marsalis-Bothers, Julian Joseph, John McLaughlin, Larry Coryell, Art Farmer, Joanne Brackeen, Kevin Eubanks, Gary Thomas, McCoy Tyner, Joe Zawinul, Barbara Dennerlein, John Scofield, John Serry, Orphy Robinson and theLoose Tubes.

In additon he also played with Jethro Tull, Jeff Beck, Van Morrison, Brian Ferry, Keith More and Ronnie Wood.

Mark Mondesir is the brother of bassguitarist Michael Mondesir.

Dennis Chambers counts him to the greatest drummers he ever saw - same said also the legendary Tony Williams....